BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuGilbert syndromeIcterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign bilirubinemia; Gilbert diseaseGilbert syndrome is a common disorder passed down through families. It affects the way bilirubin is processed by the liver, and may cause the skin to take on a yellow color (jaundice) at times.JaundiceJaundice is a yellow color of the skin, mucus membranes, or eyes. The yellow coloring comes from bilirubin, a byproduct of old red blood cells. Jau...ImageRead Article Now Book Mark Article Causes Gilbert syndrome affects 1 in 10 people in some white groups. This condition occurs due to an abnormal gene, which is passed from parents to their children. Symptoms Symptoms may include:Fatigue Yellowing of the skin and whites of the eyes (mild jaundice) In people with Gilbert syndrome, jaundice most often appears during times of exertion, stress, and infection, or when they do not eat. Exams and Tests A blood test for bilirubin shows changes that occur with Gilbert syndrome. The total bilirubin level is mildly elevated, with most being unconjugated bilirubin. Most often the total level is less than 2 mg/dL, and the conjugated bilirubin level is normal.Gilbert syndrome is linked to a genetic problem, but genetic testing is not needed. Treatment No treatment is necessary for Gilbert syndrome. Outlook (Prognosis) Jaundice may come and go throughout life. It is more likely to appear during illnesses such as colds. It does not cause health problems. However, it can confuse the results of tests for jaundice. Possible Complications There are no known complications. When to Contact a Medical Professional Call your health care provider if you have jaundice or pain in the abdomen that does not go away. Prevention There is no proven prevention.Open ReferencesReferencesKorenblat KM, Berk PD. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 138.Lidofsky SD. Jaundice. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 21.Quaglia A, Roberts EA, Torbenson M. Developmental and inherited liver disease. In: Burt AD, Ferrell LD, Hübscher SG, eds. MacSween's Pathology of the Liver. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 3.AllVideoImagesTogDigestive system - illustration The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.Digestive systemillustrationDigestive system - illustration The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.Digestive systemillustrationRelated Information Bilirubin blood test(Medical Test)Benign(Special Topic)Hepatitis(In-Depth) Review Date: 4/21/2021 Reviewed By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.