BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuLeydig cell testicular tumorTumor - Leydig cell; Testicular tumor - LeydigA Leydig cell tumor is a tumor of the testicle. It develops from Leydig cells. These are the cells in the testicles that release the male hormone, testosterone.TumorA tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).Read Article Now Book Mark Article TestosteroneA testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. The test described...Read Article Now Book Mark Article Causes The cause of this tumor is unknown. There are no known risk factors for this tumor. Unlike germ cell tumors of the testicles, this tumor does not seem to be linked to undescended testes.Undescended testesUndescended testicle occurs when one or both testicles fail to move into the scrotum before birth.ImageRead Article Now Book Mark Article Leydig cell tumors make up a very small number of all testicular tumors. They are most often found in men between 30 and 60 years of age. This tumor is not common in children before puberty, but it may cause early puberty.Early pubertyPuberty is the time when a person's sexual and physical characteristics mature. Precocious puberty is when these body changes happen earlier than no...ImageRead Article Now Book Mark Article Symptoms There may be no symptoms.When symptoms do occur, they can include:Discomfort or pain in the testicle Enlargement of a testicle or change in the way it feels Excess growth of breast tissue (gynecomastia) -- however, this can occur normally in adolescent boys who do not have testicular cancer GynecomastiaWhen abnormal breast tissue develops in males, it is called gynecomastia. It is important to find out if the excess growth is breast tissue and not ...ImageRead Article Now Book Mark Article Heaviness in the scrotum Lump or swelling in either testicle Pain in the lower abdomen or back Not able to father children (infertility)Symptoms in other parts of the body, such as the lungs, abdomen, pelvis, back, or brain may also occur if the cancer has spread. Exams and Tests A physical examination typically reveals a firm lump in one of the testicles. When the health care provider holds a flashlight up to the scrotum, the light does not pass through the lump. This test is called transillumination.TransilluminationTransillumination is the shining of a light through a body area or organ to check for abnormalities.ImageRead Article Now Book Mark Article Other tests include:Blood tests for tumor markers: alpha fetoprotein (AFP), human chorionic gonadotropin (beta HCG), and lactate dehydrogenase (LDH) Alpha fetoproteinAlpha fetoprotein (AFP) is a protein produced by the liver and yolk sac of a developing baby during pregnancy. AFP levels go down soon after birth. ...ImageRead Article Now Book Mark Article Human chorionic gonadotropinA quantitative human chorionic gonadotropin (HCG) test measures the specific level of HCG in the blood. HCG is a hormone produced in the body during...ImageRead Article Now Book Mark Article Lactate dehydrogenaseThe lactate dehydrogenase (LDH) isoenzyme test checks how much of the different types of LDH are in the blood.ImageRead Article Now Book Mark Article CT scan of the chest, abdomen and pelvis to check if the cancer has spread CT scan of the chest, abdomenAn abdominal CT scan is an imaging method. This test uses x-rays to create cross-sectional pictures of the belly area. CT stands for computed tomog...ImageRead Article Now Book Mark Article Ultrasound of the scrotumUltrasoundUltrasound uses high-frequency sound waves to make images of organs and structures inside the body.ImageRead Article Now Book Mark Article An examination of the tissue is usually done after the entire testicle is surgically removed (orchiectomy). Treatment Treatment of a Leydig cell tumor depends on its stage.Stage I cancer has not spread beyond the testicle. Stage II cancer has spread to lymph nodes in the abdomen. Stage III cancer has spread beyond the lymph nodes (possibly as far as the liver, lungs, or brain).Surgery is done to remove the testicle (orchiectomy). Nearby lymph nodes may also be removed (lymphadenectomy).Chemotherapy may be used to treat this tumor. As Leydig cell tumors are rare, these treatments have not been studied as much as treatments for other, more common testicular cancers.ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancer Shrink the cancerPrevent the cancer from...ImageRead Article Now Book Mark Article Support Groups Joining a support group where members share common experiences and problems can often help ease the stress of illness.Support groupThe following organizations are good resources for information on cancer:American Cancer Society -- www. cancer. orgAmerican Childhood Cancer Organiz...Read Article Now Book Mark Article Outlook (Prognosis) Testicular cancer is one of the most treatable and curable cancers. Outlook is worse if the tumor is not found early. Possible Complications The cancer may spread to other parts of the body. The most common sites include the:Abdomen Lungs Retroperitoneal area (the area near the kidneys behind the other organs in the belly area) Spine Complications of surgery can include:Bleeding and infection Infertility (if both testicles are removed) InfertilityInfertility means you cannot get pregnant (conceive). There are 2 types of infertility:Primary infertility refers to couples who have not become preg...ImageRead Article Now Book Mark Article If you are of childbearing age, ask your provider about methods to save your sperm for use at a later date. When to Contact a Medical Professional Call your provider if you have symptoms of testicular cancer. Prevention Performing testicular self-examination (TSE) each month may help detect testicular cancer at an early stage, before it spreads. Finding testicular cancer early is important for successful treatment and survival.Testicular self-examination (TSE)Testicular self-exam is an examination of the testicles that you do on yourself.ImageRead Article Now Book Mark Article Open ReferencesReferencesFriedlander TW, Small E. Testicular cancer. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 83.National Cancer Institute website. Testicular cancer treatment (PDQ) – health professional version. www.cancer.gov/types/testicular/hp/testicular-treatment-pdq. Updated May 21, 2020. Accessed July 21, 2020.Stephenson AJ, Gilligan TD. Neoplasms of the testis. In: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; 2021:chap 76.AllVideoImagesTogMale reproductive anatomy - illustration The male reproductive structures include the penis, the scrotum, the testicles (testes), the epididymis, the seminal vesicles, and the prostate.Male reproductive anatomyillustrationMale reproductive anatomy - illustration The male reproductive structures include the penis, the scrotum, the testicles (testes), the epididymis, the seminal vesicles, and the prostate.Male reproductive anatomyillustrationRelated Information Tumor(Condition)Testosterone(Medical Test) Review Date: 5/27/2020 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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