BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuTabes dorsalisLocomotor ataxia; Syphilitic myelopathy; Syphilitic myeloneuropathy; Myelopathy - syphilitic; Tabetic neurosyphilisTabes dorsalis is a complication of untreated syphilis that involves muscle weakness and abnormal sensations.SyphilisSyphilis is a bacterial infection that is most often spread through sexual contact.ImageRead Article Now Book Mark Article Causes Tabes dorsalis is a form of neurosyphilis, which is a complication of late stage syphilis infection. Syphilis is a bacterial infection that is spread sexually.NeurosyphilisNeurosyphilis is a bacterial infection of the brain or spinal cord. It usually occurs in people who have had untreated syphilis for many years....ImageRead Article Now Book Mark Article When syphilis is untreated, the bacteria damages the spinal cord and peripheral nervous tissue. This leads to the symptoms of tabes dorsalis.PeripheralPeripheral means "away from the center. " It refers to areas away from the center of the body or a body part. For example, the hands are peripheral ...ImageRead Article Now Book Mark Article Tabes dorsalis is now very rare because syphilis is usually treated early in the disease. Symptoms Symptoms of tabes dorsalis are caused by damage to the nervous system. Symptoms include any of the following:Abnormal sensations (paresthesia), often called "lightning pains" ParesthesiaNumbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...ImageRead Article Now Book Mark Article Problems walking such as with the legs far apart Loss of coordination and reflexes Joint damage, especially of the knees Muscle weakness Vision changes Bladder control problems Sexual function problems Exams and Tests The health care provider will perform a physical exam, focusing on the nervous system.Physical examDuring a physical examination, a health care provider studies your body to determine if you do or do not have a physical problem. A physical examinat...Read Article Now Book Mark Article If syphilis infection is suspected, tests may include the following:Cerebrospinal fluid (CSF) examination Cerebrospinal fluid (CSF) examinationA CSF cell count is a test to measure the number of red and white blood cells that are in cerebrospinal fluid (CSF). CSF is a clear fluid that is in...ImageRead Article Now Book Mark Article Head CT, spine CT, or MRI scans of the brain and spinal cord to rule out other diseases Head CTA head computed tomography (CT) scan uses many x-rays to create pictures of the head, including the skull, brain, eye sockets, and sinuses.ImageRead Article Now Book Mark Article Spine CTA lumbosacral spine CT is a computed tomography scan of the lower spine and surrounding tissues.ImageRead Article Now Book Mark Article MRIA magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...ImageRead Article Now Book Mark Article Serum VDRL or serum RPR (used as a screening test for syphilis infection)Serum VDRLThe VDRL test is a screening test for syphilis. It measures substances (proteins), called antibodies, which your body may produce if you have come i...ImageRead Article Now Book Mark Article RPRRPR (rapid plasma reagin) is a screening test for syphilis. It measures substances (proteins) called antibodies that are present in the blood of peo...ImageRead Article Now Book Mark Article If the serum VDRL or serum RPR test is positive, one of the following tests will be needed to confirm the diagnosis: FTA-ABS FTA-ABSThe FTA-ABS test is used to detect antibodies to the bacteria Treponema pallidum, which causes syphilis.ImageRead Article Now Book Mark Article MHA-TP TP-EIA TP-PA Treatment The goals of treatment are to cure the infection and slow the disease. Treating the infection helps prevent new nerve damage and may reduce symptoms. Treatment does not reverse existing nerve damage.Medicines likely to be given include:Penicillin or other antibiotics for a long time to make sure the infection goes away Painkillers to control painSymptoms of existing nervous system damage need to be treated. People who are unable to eat, dress themselves, or take care of themselves may need help. Rehabilitation, physical therapy, and occupational therapy may help with muscle weakness. Outlook (Prognosis) Left untreated, tabes dorsalis may lead to disability. Possible Complications Complications may include:Blindness Paralysis When to Contact a Medical Professional Call your provider if you have: Loss of coordination Loss of coordinationUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article Loss of muscle strength Loss of sensationLoss of sensationNumbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...ImageRead Article Now Book Mark Article Prevention Proper treatment and follow-up of syphilis infections reduces the risk of developing tabes dorsalis.If you are sexually active, practice safer sex and always use a condom.Practice safer sexSafe sex means taking steps before and during sex that can prevent you from getting an infection, or from giving an infection to your partner....ImageRead Article Now Book Mark Article All pregnant women should be screened for syphilis.Open ReferencesReferencesGhanem KG, Hook EW. Syphilis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 303.Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 237.AllVideoImagesTogSuperficial anterior muscles - illustration Superficial muscles are close to the surface of the skin. Muscles which lie closer to bone or internal organs are called deep muscles.Superficial anterior musclesillustrationPrimary syphilis - illustration Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. Primary syphilis presents as a small painless open sore 3 to 6 weeks after exposure. Although the lesion heals within 6 to 8 weeks, the untreated organism will continue to multiply unchecked, causing many complications. Infection may last for 30 years or more and result in severe neurological complications.Primary syphilisillustrationLate-stage syphilis - illustration Tertiary syphilis is a late stage of the disease which can follow the initial infection, primary syphilis, by several years. Pockets of damage accumulate in various tissues such as the bones, skin, nervous tissue, heart, and arteries. These lesions are called gummas and are very destructive.Late-stage syphilisillustrationSuperficial anterior muscles - illustration Superficial muscles are close to the surface of the skin. Muscles which lie closer to bone or internal organs are called deep muscles.Superficial anterior musclesillustrationPrimary syphilis - illustration Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. Primary syphilis presents as a small painless open sore 3 to 6 weeks after exposure. Although the lesion heals within 6 to 8 weeks, the untreated organism will continue to multiply unchecked, causing many complications. Infection may last for 30 years or more and result in severe neurological complications.Primary syphilisillustrationLate-stage syphilis - illustration Tertiary syphilis is a late stage of the disease which can follow the initial infection, primary syphilis, by several years. Pockets of damage accumulate in various tissues such as the bones, skin, nervous tissue, heart, and arteries. These lesions are called gummas and are very destructive.Late-stage syphilisillustrationRelated Information Weakness(Symptoms)Numbness and tingling(Symptoms)Neurosyphilis(Condition)Peripheral(Special Topic)Walking abnormalities(Symptoms)Abdominal aortic aneurysm(Condition) Review Date: 10/25/2020 Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. 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Tabes dorsalisLocomotor ataxia; Syphilitic myelopathy; Syphilitic myeloneuropathy; Myelopathy - syphilitic; Tabetic neurosyphilisTabes dorsalis is a complication of untreated syphilis that involves muscle weakness and abnormal sensations.SyphilisSyphilis is a bacterial infection that is most often spread through sexual contact.ImageRead Article Now Book Mark Article Causes Tabes dorsalis is a form of neurosyphilis, which is a complication of late stage syphilis infection. Syphilis is a bacterial infection that is spread sexually.NeurosyphilisNeurosyphilis is a bacterial infection of the brain or spinal cord. It usually occurs in people who have had untreated syphilis for many years....ImageRead Article Now Book Mark Article When syphilis is untreated, the bacteria damages the spinal cord and peripheral nervous tissue. This leads to the symptoms of tabes dorsalis.PeripheralPeripheral means "away from the center. " It refers to areas away from the center of the body or a body part. For example, the hands are peripheral ...ImageRead Article Now Book Mark Article Tabes dorsalis is now very rare because syphilis is usually treated early in the disease. Symptoms Symptoms of tabes dorsalis are caused by damage to the nervous system. Symptoms include any of the following:Abnormal sensations (paresthesia), often called "lightning pains" ParesthesiaNumbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...ImageRead Article Now Book Mark Article Problems walking such as with the legs far apart Loss of coordination and reflexes Joint damage, especially of the knees Muscle weakness Vision changes Bladder control problems Sexual function problems Exams and Tests The health care provider will perform a physical exam, focusing on the nervous system.Physical examDuring a physical examination, a health care provider studies your body to determine if you do or do not have a physical problem. A physical examinat...Read Article Now Book Mark Article If syphilis infection is suspected, tests may include the following:Cerebrospinal fluid (CSF) examination Cerebrospinal fluid (CSF) examinationA CSF cell count is a test to measure the number of red and white blood cells that are in cerebrospinal fluid (CSF). CSF is a clear fluid that is in...ImageRead Article Now Book Mark Article Head CT, spine CT, or MRI scans of the brain and spinal cord to rule out other diseases Head CTA head computed tomography (CT) scan uses many x-rays to create pictures of the head, including the skull, brain, eye sockets, and sinuses.ImageRead Article Now Book Mark Article Spine CTA lumbosacral spine CT is a computed tomography scan of the lower spine and surrounding tissues.ImageRead Article Now Book Mark Article MRIA magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...ImageRead Article Now Book Mark Article Serum VDRL or serum RPR (used as a screening test for syphilis infection)Serum VDRLThe VDRL test is a screening test for syphilis. It measures substances (proteins), called antibodies, which your body may produce if you have come i...ImageRead Article Now Book Mark Article RPRRPR (rapid plasma reagin) is a screening test for syphilis. It measures substances (proteins) called antibodies that are present in the blood of peo...ImageRead Article Now Book Mark Article If the serum VDRL or serum RPR test is positive, one of the following tests will be needed to confirm the diagnosis: FTA-ABS FTA-ABSThe FTA-ABS test is used to detect antibodies to the bacteria Treponema pallidum, which causes syphilis.ImageRead Article Now Book Mark Article MHA-TP TP-EIA TP-PA Treatment The goals of treatment are to cure the infection and slow the disease. Treating the infection helps prevent new nerve damage and may reduce symptoms. Treatment does not reverse existing nerve damage.Medicines likely to be given include:Penicillin or other antibiotics for a long time to make sure the infection goes away Painkillers to control painSymptoms of existing nervous system damage need to be treated. People who are unable to eat, dress themselves, or take care of themselves may need help. Rehabilitation, physical therapy, and occupational therapy may help with muscle weakness. Outlook (Prognosis) Left untreated, tabes dorsalis may lead to disability. Possible Complications Complications may include:Blindness Paralysis When to Contact a Medical Professional Call your provider if you have: Loss of coordination Loss of coordinationUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article Loss of muscle strength Loss of sensationLoss of sensationNumbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...ImageRead Article Now Book Mark Article Prevention Proper treatment and follow-up of syphilis infections reduces the risk of developing tabes dorsalis.If you are sexually active, practice safer sex and always use a condom.Practice safer sexSafe sex means taking steps before and during sex that can prevent you from getting an infection, or from giving an infection to your partner....ImageRead Article Now Book Mark Article All pregnant women should be screened for syphilis.Open ReferencesReferencesGhanem KG, Hook EW. Syphilis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 303.Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 237.
