BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPenile cancerCancer - penis; Squamous cell cancer - penis; Glansectomy; Partial penectomyPenile cancer is cancer that starts in the penis, an organ that makes up part of the male reproductive system. CancerCancer is the uncontrolled growth of abnormal cells in the body. Cancerous cells are also called malignant cells.Read Article Now Book Mark Article PenisThe penis is the male organ used for urination and sexual intercourse. The penis is located above the scrotum. It is made of spongy tissue and bloo...ImageRead Article Now Book Mark Article Causes Cancer of the penis is rare. Its exact cause is unknown. However, certain risk factors include:Uncircumcised men who don't keep the area under the foreskin clean. This leads to buildup of smegma, a cheese-like, foul-smelling substance under the foreskin. History of genital warts, or human papillomavirus (HPV). Smoking. Injury to the penis. The cancer usually affects middle age and older men. Symptoms Early symptoms may include:Sore, bump, rash, or swelling at the tip or on the shaft of the penis Foul-smelling discharge beneath the foreskinAs the cancer advances, symptoms may include:Pain and bleeding from the penis (may occur with advanced disease) Lumps in the groin area from spread of the cancer to the groin lymph nodes Weight loss Difficulty in passing urine Exams and Tests The health care provider will perform a physical exam and ask about your health history and symptoms.A biopsy of the growth is needed to determine if it is cancer.BiopsyA biopsy is the removal of a small piece of tissue for laboratory examination.Read Article Now Book Mark Article Treatment Treatment depends on the size and location of the tumor and how much it has spread.Treatment for penile cancer may include:Chemotherapy -- uses medicines to kill cancer cells Radiation -- uses high-powered x-rays to kill cancer cells Surgery - cuts out and removes the cancer If the tumor is small or near the tip of the penis, surgery may be done to remove only the cancerous part of the penis where the cancer is found. Depending on the exact location, this is called a glansectomy or partial penectomy. Laser surgery may be used to treat some tumors.For more severe tumors, total removal of the penis (total penectomy) is often needed. A new opening will be created in the groin area to allow urine to exit the body. This procedure is called a urethrostomy.Chemotherapy may be used along with surgery. ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancer Shrink the cancerPrevent the cancer from...ImageRead Article Now Book Mark Article Radiation therapy may be used along with surgery. A type of radiation therapy called external beam therapy is often used. This method delivers radiation to the penis from outside the body. This therapy is most often performed 5 days a week for 6 to 8 weeks.Radiation therapyRadiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.ImageRead Article Now Book Mark Article Outlook (Prognosis) The outcome can be good with early diagnosis and treatment. Urination and sexual function can often be maintained. Possible Complications Untreated, penile cancer can spread to other parts of the body (metastasize) early in the disease.MetastasizeMetastasis is the movement or spreading of cancer cells from one organ or tissue to another. Cancer cells usually spread through the blood or the ly...ImageRead Article Now Book Mark Article When to Contact a Medical Professional Call your provider if symptoms of penile cancer develop. Prevention Circumcision may decrease the risk. Men who are not circumcised should be taught at an early age the importance of cleaning beneath the foreskin as part of their personal hygiene.Safer sexual practices, such as abstinence, limiting the number of sexual partners, and using condoms to prevent HPV infection, may decrease the risk of developing cancer of the penis.Safer sexual practicesSafe sex means taking steps before and during sex that can prevent you from getting an infection, or from giving an infection to your partner....ImageRead Article Now Book Mark Article Open ReferencesReferencesHeinlen JE, Ramadan MO, Stratton K, Culkin DJ. Cancer of the penis. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 82.National Cancer Institute website. Penile cancer treatment (PDQ) - health professional version. www.cancer.gov/types/penile/hp/penile-treatment-pdq#link/_1. Updated August 3, 2020. Accessed October 14, 2020.AllVideoImagesTogMale reproductive anatomy - illustration The male reproductive structures include the penis, the scrotum, the testicles (testes), the epididymis, the seminal vesicles, and the prostate.Male reproductive anatomyillustrationMale reproductive system - illustration The male reproductive system, viewed from a sagittal section.Male reproductive systemillustrationMale reproductive anatomy - illustration The male reproductive structures include the penis, the scrotum, the testicles (testes), the epididymis, the seminal vesicles, and the prostate.Male reproductive anatomyillustrationMale reproductive system - illustration The male reproductive system, viewed from a sagittal section.Male reproductive systemillustrationRelated Information Cancer(Condition)Genital warts(Condition) Review Date: 7/28/2020 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. 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