BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPost-splenectomy complicationsSplenectomy - post-surgery syndrome; Overwhelming post-splenectomy infection; OPSI; Splenectomy - reactive thrombocytosisPost-splenectomy complications can occur after surgery to remove the spleen. Complications may include: Blood clots Destruction of red blood cells Destruction of red blood cellsHemolysis is the breakdown of red blood cells.Read Article Now Book Mark Article Increased risk for severe infections from bacteria such as Streptococcus pneumoniae and Neisseria meningitidis Thrombocytosis (increased platelet count, which can cause blood clots) Platelet countA platelet count is a lab test to measure how many platelets you have in your blood. Platelets are parts of the blood that help the blood clot. The...Read Article Now Book Mark Article Blood clotsBlood clots are clumps that occur when blood hardens from a liquid to a solid. A blood clot that forms inside one of your veins or arteries is calle...ImageRead Article Now Book Mark Article Possible Complications Possible long-term medical problems include:Hardening of the arteries (atherosclerosis) AtherosclerosisAtherosclerosis, sometimes called "hardening of the arteries," occurs when fat, cholesterol, and other substances build up in the walls of arteries. ...ImageRead Article Now Book Mark Article Pulmonary hypertension (a disease affecting the blood vessels in your lungs) Pulmonary hypertensionPulmonary hypertension is high blood pressure in the arteries of the lungs. It makes the right side of the heart work harder than normal.ImageRead Article Now Book Mark Article Open ReferencesReferencesConnell NT, Shurin SB, Schiffman F. The spleen and its disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 160.Croce MA, Fitzgerald M. The injured spleen. In: Cameron AM, Cameron JL, eds. Current Surgical Therapy. 13th ed. Philadelphia, PA: Elsevier; 2020:1194-1196.Nassar AK, Hawn M. The spleen. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 57.AllVideoImagesTogSpleen - illustration The spleen is an organ involved in the production and maintenance of red blood cells, the production of certain circulating white blood cells, as a part of the lymph system, and as a part of the immune system.SpleenillustrationSpleen - illustration The spleen is an organ involved in the production and maintenance of red blood cells, the production of certain circulating white blood cells, as a part of the lymph system, and as a part of the immune system.SpleenillustrationA Closer Look Hodgkin disease(In-Depth)Leukemia(Alt. Medicine)Related Information Spleen removal(Surgery)Platelet count(Medical Test)Blood clots(Condition)Hemolysis(Special Topic) Review Date: 1/19/2021 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.