BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuGanglioneuroblastomaGanglioneuroblastoma is an intermediate tumor that arises from nerve tissues. An intermediate tumor is one that is between benign (slow-growing and unlikely to spread) and malignant (fast-growing, aggressive, and likely to spread). Causes Ganglioneuroblastoma mostly occurs in children ages 2 to 4 years. The tumor affects boys and girls equally. It occurs rarely in adults. Tumors of the nervous system have different degrees of differentiation. This is based on how the tumor cells look under the microscope. It can predict whether or not they are likely to spread.Benign tumors are less likely to spread. Malignant tumors are aggressive, grow quickly, and often spread. A ganglioneuroma is less malignant in nature. A neuroblastoma (occurring in children over 1 year old) is usually malignant.GanglioneuromaGanglioneuroma is a tumor of the autonomic nervous system.Read Article Now Book Mark Article NeuroblastomaNeuroblastoma is a very rare type of cancerous tumor that develops from nerve tissue. It usually occurs in infants and children.Read Article Now Book Mark Article A ganglioneuroblastoma may be only in one area or it may be widespread, but it is usually less aggressive than a neuroblastoma. The cause is unknown. Symptoms Most commonly, a lump can be felt in the abdomen with tenderness.This tumor may also occur at other sites, including:Chest cavity Neck Legs Exams and Tests The health care provider may do the following tests:Fine-needle aspiration of the tumor Bone marrow aspiration and biopsy AspirationBone marrow is the soft tissue inside bones that helps form blood cells. It is found in the hollow part of most bones. Bone marrow aspiration is th...Read Article Now Book Mark Article BiopsyA bone marrow biopsy is the removal of marrow from inside bone. Bone marrow is the soft tissue inside bones that helps form blood cells. It is foun...Read Article Now Book Mark Article Bone scan CT scan or MRI scan of the affected area PET scan Metaiodobenzylguanidine (MIBG) scan Metaiodobenzylguanidine (MIBG) scanAn MIBG scintiscan is a type of imaging test. It uses a radioactive substance (called a tracer). A scanner finds or confirms the presence of pheoch...Read Article Now Book Mark Article Special blood and urine tests Surgical biopsy to confirm diagnosis Treatment Depending on the type of tumor, treatment can involve surgery, and possibly chemotherapy and radiation therapy.Because these tumors are rare, they should be treated in a specialized center by experts who have experience with them. Support Groups More information and support for children with ganglioneuroblastoma and their families can be found at:Children's Oncology Group -- www.childrensoncologygroup.org The Neuroblastoma Children's Cancer Society -- neuroblastomachildrenscancersociety.org/ Outlook (Prognosis) The outlook depends on how far the tumor has spread, and whether some areas of the tumor contain more aggressive cancer cells. Possible Complications Complications that may result include:Complications of surgery, radiation, or chemotherapy RadiationRadiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.Read Article Now Book Mark Article ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancer Shrink the cancerPrevent the cancer from...Read Article Now Book Mark Article Spread of the tumor into surrounding areas When to Contact a Medical Professional Contact your provider if you feel a lump or growth on your child's body. Make sure children receive routine examinations as part of their well-child care.Open ReferencesReferencesHarrison DJ, Ater JL. Neuroblastoma. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 525.Myers JL. Mediastinum. In: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. Rosai and Ackerman's Surgical Pathology. 11th ed. Philadelphia, PA: Elsevier; 2018:chap 12.AllVideoImagesTogRelated Information Review Date: 10/28/2021 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. 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GanglioneuroblastomaGanglioneuroblastoma is an intermediate tumor that arises from nerve tissues. An intermediate tumor is one that is between benign (slow-growing and unlikely to spread) and malignant (fast-growing, aggressive, and likely to spread). Causes Ganglioneuroblastoma mostly occurs in children ages 2 to 4 years. The tumor affects boys and girls equally. It occurs rarely in adults. Tumors of the nervous system have different degrees of differentiation. This is based on how the tumor cells look under the microscope. It can predict whether or not they are likely to spread.Benign tumors are less likely to spread. Malignant tumors are aggressive, grow quickly, and often spread. A ganglioneuroma is less malignant in nature. A neuroblastoma (occurring in children over 1 year old) is usually malignant.GanglioneuromaGanglioneuroma is a tumor of the autonomic nervous system.Read Article Now Book Mark Article NeuroblastomaNeuroblastoma is a very rare type of cancerous tumor that develops from nerve tissue. It usually occurs in infants and children.Read Article Now Book Mark Article A ganglioneuroblastoma may be only in one area or it may be widespread, but it is usually less aggressive than a neuroblastoma. The cause is unknown. Symptoms Most commonly, a lump can be felt in the abdomen with tenderness.This tumor may also occur at other sites, including:Chest cavity Neck Legs Exams and Tests The health care provider may do the following tests:Fine-needle aspiration of the tumor Bone marrow aspiration and biopsy AspirationBone marrow is the soft tissue inside bones that helps form blood cells. It is found in the hollow part of most bones. Bone marrow aspiration is th...Read Article Now Book Mark Article BiopsyA bone marrow biopsy is the removal of marrow from inside bone. Bone marrow is the soft tissue inside bones that helps form blood cells. It is foun...Read Article Now Book Mark Article Bone scan CT scan or MRI scan of the affected area PET scan Metaiodobenzylguanidine (MIBG) scan Metaiodobenzylguanidine (MIBG) scanAn MIBG scintiscan is a type of imaging test. It uses a radioactive substance (called a tracer). A scanner finds or confirms the presence of pheoch...Read Article Now Book Mark Article Special blood and urine tests Surgical biopsy to confirm diagnosis Treatment Depending on the type of tumor, treatment can involve surgery, and possibly chemotherapy and radiation therapy.Because these tumors are rare, they should be treated in a specialized center by experts who have experience with them. Support Groups More information and support for children with ganglioneuroblastoma and their families can be found at:Children's Oncology Group -- www.childrensoncologygroup.org The Neuroblastoma Children's Cancer Society -- neuroblastomachildrenscancersociety.org/ Outlook (Prognosis) The outlook depends on how far the tumor has spread, and whether some areas of the tumor contain more aggressive cancer cells. Possible Complications Complications that may result include:Complications of surgery, radiation, or chemotherapy RadiationRadiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.Read Article Now Book Mark Article ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancer Shrink the cancerPrevent the cancer from...Read Article Now Book Mark Article Spread of the tumor into surrounding areas When to Contact a Medical Professional Contact your provider if you feel a lump or growth on your child's body. Make sure children receive routine examinations as part of their well-child care.Open ReferencesReferencesHarrison DJ, Ater JL. Neuroblastoma. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 525.Myers JL. Mediastinum. In: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. Rosai and Ackerman's Surgical Pathology. 11th ed. Philadelphia, PA: Elsevier; 2018:chap 12.