BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuProchlorperazine overdoseProchlorperazine is a drug used to treat severe nausea and vomiting. It is a member of the class of medicines called phenothiazines, some of which are used to treat mental disturbances. Prochlorperazine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the normal or recommended amount of something, often a drug. An overdose may result in serious, harmful sympt...Read Article Now Book Mark Article Poisonous Ingredient Prochlorperazine can be poisonous in large amounts. Where Found Prochlorperazine is found in these products:Compazine Compro Symptoms Below are symptoms of prochlorperazine overdose in different parts of the body.AIRWAYS AND LUNGSNo breathing Rapid breathing Shallow breathing BLADDER AND KIDNEYSDifficult or slow urination Inability to completely empty the bladder EYES, EARS, NOSE, MOUTH, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Difficulty swallowing Drooling Dry mouth Nasal congestion Small or large pupils Sores in the mouth, on the tongue or in the throat Yellow eyes due to jaundice HEART AND BLOODLow blood pressure (severe) Pounding heartbeat Rapid heartbeatRapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article MUSCLES AND JOINTSMuscle spasms Muscle stiffness Rapid, involuntary movements of the face (chewing, blinking, grimaces, and tongue movements) NERVOUS SYSTEMAgitation, irritability, confusion Convulsions (seizures) ConvulsionsA seizure is the physical changes in behavior that occurs during an episode of abnormal electrical activity in the brain. The term "seizure" is often...Read Article Now Book Mark Article Disorientation, coma Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep in when they do not want to or at times w...Read Article Now Book Mark Article Fever Low body temperature Restlessness linked with repeated foot shuffling, rocking, or pacing Tremor, motor tics that the person cannot control Uncoordinated movement, slow movement, or shuffling (with long-term use or overuse) Uncoordinated movementUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article Weakness REPRODUCTIVE SYSTEMChanges in menstrual patterns SKINRash Sun sensitivity, rapid sunburn Skin color changesSTOMACH AND INTESTINESConstipation Loss of appetite Loss of appetiteA decreased appetite is when your desire to eat is reduced. The medical term for a loss of appetite is anorexia.Read Article Now Book Mark Article NauseaSome of these symptoms may occur, even when the medicine is taken properly. Before Calling Emergency Have this information ready: Person's age, weight, and condition The name of the product (ingredients and strengths, if known) When it was swallowed The amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container with you to the hospital, if possible.The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests CT scan (computerized axial tomography or advanced brain imaging) Chest x-ray ECG (electrocardiogram, or heart tracing) Treatment may include:Fluids through a vein (by IV) Medicine to treat symptoms Laxative Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator) Outlook (Prognosis) Prochlorperazine is fairly safe. Most likely, an overdose will only cause drowsiness and some side effects, such as uncontrolled movements of the lips, eyes, head, and neck for a short time. These movements may continue if they are not treated quickly and correctly.In rare cases, an overdose can cause more serious symptoms. Nervous system symptoms may be permanent. The most serious side effects are usually due to damage to the heart. If heart damage can be stabilized, recovery is likely. Life-threatening heart rhythm disturbances may be difficult to treat, and may result in death. Survival past 2 days is usually a good sign Open ReferencesReferencesAronson JK. Prochlorperazine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:954-955.Skolnik AB, Monas J. Antipsychotics. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 155.AllVideoImagesTogRelated Information Review Date: 7/20/2021 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. 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Prochlorperazine overdoseProchlorperazine is a drug used to treat severe nausea and vomiting. It is a member of the class of medicines called phenothiazines, some of which are used to treat mental disturbances. Prochlorperazine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the normal or recommended amount of something, often a drug. An overdose may result in serious, harmful sympt...Read Article Now Book Mark Article Poisonous Ingredient Prochlorperazine can be poisonous in large amounts. Where Found Prochlorperazine is found in these products:Compazine Compro Symptoms Below are symptoms of prochlorperazine overdose in different parts of the body.AIRWAYS AND LUNGSNo breathing Rapid breathing Shallow breathing BLADDER AND KIDNEYSDifficult or slow urination Inability to completely empty the bladder EYES, EARS, NOSE, MOUTH, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Difficulty swallowing Drooling Dry mouth Nasal congestion Small or large pupils Sores in the mouth, on the tongue or in the throat Yellow eyes due to jaundice HEART AND BLOODLow blood pressure (severe) Pounding heartbeat Rapid heartbeatRapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article MUSCLES AND JOINTSMuscle spasms Muscle stiffness Rapid, involuntary movements of the face (chewing, blinking, grimaces, and tongue movements) NERVOUS SYSTEMAgitation, irritability, confusion Convulsions (seizures) ConvulsionsA seizure is the physical changes in behavior that occurs during an episode of abnormal electrical activity in the brain. The term "seizure" is often...Read Article Now Book Mark Article Disorientation, coma Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep in when they do not want to or at times w...Read Article Now Book Mark Article Fever Low body temperature Restlessness linked with repeated foot shuffling, rocking, or pacing Tremor, motor tics that the person cannot control Uncoordinated movement, slow movement, or shuffling (with long-term use or overuse) Uncoordinated movementUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article Weakness REPRODUCTIVE SYSTEMChanges in menstrual patterns SKINRash Sun sensitivity, rapid sunburn Skin color changesSTOMACH AND INTESTINESConstipation Loss of appetite Loss of appetiteA decreased appetite is when your desire to eat is reduced. The medical term for a loss of appetite is anorexia.Read Article Now Book Mark Article NauseaSome of these symptoms may occur, even when the medicine is taken properly. Before Calling Emergency Have this information ready: Person's age, weight, and condition The name of the product (ingredients and strengths, if known) When it was swallowed The amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container with you to the hospital, if possible.The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests CT scan (computerized axial tomography or advanced brain imaging) Chest x-ray ECG (electrocardiogram, or heart tracing) Treatment may include:Fluids through a vein (by IV) Medicine to treat symptoms Laxative Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator) Outlook (Prognosis) Prochlorperazine is fairly safe. Most likely, an overdose will only cause drowsiness and some side effects, such as uncontrolled movements of the lips, eyes, head, and neck for a short time. These movements may continue if they are not treated quickly and correctly.In rare cases, an overdose can cause more serious symptoms. Nervous system symptoms may be permanent. The most serious side effects are usually due to damage to the heart. If heart damage can be stabilized, recovery is likely. Life-threatening heart rhythm disturbances may be difficult to treat, and may result in death. Survival past 2 days is usually a good sign Open ReferencesReferencesAronson JK. Prochlorperazine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:954-955.Skolnik AB, Monas J. Antipsychotics. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 155.
