BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAmitriptyline hydrochloride overdoseElavil overdose; Adepril overdose; Endep overdose; Enovil overdose; Trepiline overdoseAmitriptyline hydrochloride is a type of prescription medicine called a tricyclic antidepressant. It is used to treat depression. Amitriptyline hydrochloride overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. OverdoseAn overdose is when you take more than the normal or recommended amount of something, often a drug. An overdose may result in serious, harmful sympt...Read Article Now Book Mark Article Poisonous Ingredient Amitriptyline can be harmful in large amounts. Where Found Amitriptyline hydrochloride is a prescription medicine. It is sold under these brand names:Adepril Emitrip Enovil Trepiline Tryptanol VanatripOther medicines may also contain amitriptyline hydrochloride. Symptoms Below are symptoms of an amitriptyline hydrochloride overdose in different parts of the body. These symptoms may occur more often or be more severe in people who also take certain other medicines that affect serotonin, a chemical in the brain.AIRWAYS AND LUNGSSlowed, labored breathingSlowed, labored breathingMost people take breathing for granted. People with certain illnesses may have breathing problems that they deal with on a regular basis. This arti...Read Article Now Book Mark Article BLADDER AND KIDNEYSCannot urinate Urine does not flow easilyUrine does not flow easilyDifficulty starting or maintaining a urine stream is called urinary hesitancy.Read Article Now Book Mark Article EYES, EARS, NOSE, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Dilated (wide) pupils Eye pain in people at risk for a type of glaucoma Dry mouthHEART AND BLOODIrregular heart rate Low blood pressure Rapid heartbeat ShockShockShock is a life-threatening condition that occurs when the body is not getting enough blood flow. Lack of blood flow means the cells and organs do n...Read Article Now Book Mark Article NERVOUS SYSTEMAgitation AgitationAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Coma ComaDecreased alertness is the most severe state of reduced awareness and is a serious condition. A coma is a state of decreased alertness from which a p...Read Article Now Book Mark Article Seizures SeizuresA seizure is the physical changes in behavior that occurs during an episode of abnormal electrical activity in the brain. The term "seizure" is often...Read Article Now Book Mark Article Drowsiness Hallucinations Headache Inability to concentrate Lack of alertness (stupor) StuporDecreased alertness is the most severe state of reduced awareness and is a serious condition. A coma is a state of decreased alertness from which a p...Read Article Now Book Mark Article Muscle rigidity or stiffness of the limbs Muscle rigidityMuscle cramps are when a muscle gets tight (contracts) without you trying to tighten it, and it does not relax. Cramps may involve all or part of on...Read Article Now Book Mark Article Restlessness RestlessnessAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Uncoordinated movementUncoordinated movementUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article STOMACH AND INTESTINESConstipation VomitingVomitingNausea is feeling an urge to vomit. It is often called "being sick to your stomach. "Vomiting or throwing-up is forcing the contents of the stomach ...Read Article Now Book Mark Article Home Care This can be a very serious overdose. Seek medical help right away. Before Calling Emergency Have this information ready: Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible. The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests CT scan Chest x-ray ECG (electrocardiogram, or heart tracing)Treatment may include:Fluids through a vein (by IV) Medicine called an antidote to reverse the effects of the poison and treat symptoms, such as sodium bicarbonate or lidocaine Activated charcoal Laxatives Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator) Outlook (Prognosis) An amitriptyline hydrochloride overdose can be very serious.People who swallow too much of this drug are almost always admitted to the hospital.How well someone does depends on how much of the drug was swallowed and how quickly treatment is given. The faster a person gets medical help, the better the chance of recovery. Complications such as pneumonia, muscle damage from lying on a hard surface for a long period of time, or brain damage from lack of oxygen may result in permanent disability. Death can occur.Open ReferencesReferencesAronson JK. Tricyclic antidepressants. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:146-169.Levine MD, Ruha AM. Antidepressants. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 146.AllVideoImagesTogRelated Information Review Date: 11/13/2021 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. 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