BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPalpebral slant - eyeMongolian slantThe palpebral slant is the direction of the slant of a line that goes from the outer corner of the eye to the inner corner. Considerations The palpebral are the upper and lower eyelids, which make up the shape of the eye. A line drawn from the inner corner to the outer corner determines the slant of the eye, or palpebral slant. Slanting and a fold of skin (epicanthal fold) are normal in people of Asian descent.Epicanthal foldAn epicanthal fold is skin of the upper eyelid that covers the inner corner of the eye. The fold runs from nose to the inner side of the eyebrow....ImageRead Article Now Book Mark Article Abnormal slanting of the eye may occur with some genetic disorders and syndromes. The most common of these is Down syndrome. People with Down syndrome often also have an epicanthal fold in the inner corner of the eye. Causes Palpebral slant may not be part of any other defect. However, in some cases, it may be due to:Down syndrome Fetal alcohol syndrome Fetal alcohol syndromeFetal alcohol syndrome (FAS) is growth, mental, and physical problems that may occur in a baby when a mother drinks alcohol during pregnancy....ImageRead Article Now Book Mark Article Certain genetic disorders When to Contact a Medical Professional Contact your health care provider if:Your infant has abnormal features of the face You are worried about your infant's ability to move their eyes You notice any abnormal color, swelling, or discharge from your infant's eyes What to Expect at Your Office Visit Your provider will perform a physical exam and ask questions about your child's medical history and symptoms.An infant with an abnormal palpebral slant will usually have other symptoms of another health condition. That condition will be diagnosed based on a family history, medical history, and a physical exam.Tests to confirm a disorder may include:Chromosome studies Chromosome studiesKaryotyping is a test to examine chromosomes in a sample of cells. This test can help identify genetic problems as the cause of a disorder or diseas...ImageRead Article Now Book Mark Article Enzyme assays EnzymeEnzymes are complex proteins that cause a specific chemical change in all parts of the body. For example, they can help break down the foods we eat ...Read Article Now Book Mark Article Metabolic studies X-raysX-raysX-rays are a type of electromagnetic radiation, just like visible light. An x-ray machine sends individual x-ray particles through the body. The im...ImageRead Article Now Book Mark Article Open ReferencesReferencesKataguiri P, Kenyon KR, Batta P, Wadia HP, Sugar J. Corneal and external eye manifestations of systemic disease. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 4.25.Madan-Khetarpal S, Arnold G. Genetic disorders and dysmorphic conditions. In: Zitelli BJ, McIntire SC, Nowalk AJ, eds. Zitelli and Davis' Atlas of Pediatric Physical Diagnosis. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 1.Örge FH. Examination and common problems in the neonatal eye. In: Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine. 11th ed. Philadelphia, PA: Elsevier; 2020:chap 95.Slavotinek AM. Dysmorphology. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 128.AllVideoImagesTogPalpebral slant - illustration The direction of the slant of a line drawn from the outer corner of the eye to the inner corner is known as the palpebral slant. The most commonly recognized syndrome associated with an abnormal palpebral slant is Down syndrome. Palpebral slantillustrationPalpebral slant - illustration The direction of the slant of a line drawn from the outer corner of the eye to the inner corner is known as the palpebral slant. The most commonly recognized syndrome associated with an abnormal palpebral slant is Down syndrome. Palpebral slantillustrationRelated Information Epicanthal folds(Symptoms) Review Date: 5/24/2021 Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. 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