BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAutoimmune liver disease panelLiver disease test panel - autoimmuneAn autoimmune liver disease panel is a group of tests that is done to check for autoimmune liver disease. An autoimmune liver disease means that the body's immune system attacks the liver.These tests include:Anti-liver/kidney microsomal antibodies Anti-mitochondrial antibodies Anti-nuclear antibodies Anti-smooth muscle antibodies Serum IgGThe panel may also include other tests. Often, immune protein levels in the blood are also checked. How the Test is Performed A blood sample is taken from a vein.VeinVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article The blood sample is sent to the lab for testing. How to Prepare for the Test You do not need to take special steps before this test. How the Test will Feel You may feel slight pain or a sting when the needle is inserted to draw blood. Afterward, there may be some throbbing. Why the Test is Performed Autoimmune disorders are a possible cause of liver disease. The most common of these diseases are autoimmune hepatitis and primary biliary cholangitis (formerly called primary biliary cirrhosis).This group of tests helps your health care provider diagnose liver disease. Normal Results PROTEIN LEVELS:The normal range for protein levels in the blood will change with each laboratory. Please check with your provider for the normal ranges in your particular laboratory.ANTIBODIES:Negative results on all antibodies are normal.Note: Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. What Abnormal Results Mean Blood tests for autoimmune diseases are not wholly accurate. They can have false negative results (you have the disease, but the test is negative) and false positive results (you do not have the disease, but the test is positive).A weakly positive or low titer positive test for autoimmune disease is often not due to any disease.A positive test on the panel may be a sign of autoimmune hepatitis or other autoimmune liver disease.If the test is positive mostly for anti-mitochondrial antibodies, you are likely to have primary biliary cholangitis. If the immune proteins are high and albumin is low, you may have liver cirrhosis or chronic active hepatitis. Risks Slight risks from having blood drawn include:Excessive bleeding Fainting or feeling lightheaded FaintingFainting is a brief loss of consciousness due to a drop in blood flow to the brain. The episode most often lasts less than a couple of minutes and y...Read Article Now Book Mark Article Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesBowlus C, Assis DN, Goldberg D. Primary and secondary sclerosing cholangitis. In: Sanyal AJ, Boyer TD, Lindor KD, Terrault NA, eds. Zakim and Boyer's Hepatology. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 43.Czaja AJ. Autoimmune hepatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 90.Daniels L, Khalili M, Goldstein E, Bluth MH, Bowne WB, Pincus MR. Evaluation of liver function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia PA: Elsevier; 2022:chap 22.AllVideoImagesTogLiver - illustration The liver serves a wide variety of body functions, including detoxifying blood and producing bile that aids in digestion.LiverillustrationLiver - illustration The liver serves a wide variety of body functions, including detoxifying blood and producing bile that aids in digestion.LiverillustrationA Closer Look Hepatitis(In-Depth)Ulcerative colitis(In-Depth)Diabetes(Alt. Medicine)Anemia(In-Depth)Menopause(In-Depth)Herbal medicine(Alt. Medicine) Tests for Autoimmune liver disease panel Autoimmune liver disease panelHepatitis virus panelRelated Information Liver disease(Condition)Antibody(Special Topic)Hepatitis(Condition)Primary biliary cirrhosis(Condition)Albumin blood (serum) test(Medical Test)Cirrhosis(Condition)Hepatitis(In-Depth)Cirrhosis(In-Depth) Review Date: 1/14/2021 Reviewed By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.