BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuGrowth hormone stimulation testArginine test; Arginine - GHRH test The growth hormone (GH) stimulation test measures the ability of the body to produce GH. How the Test is Performed Blood is drawn several times. Blood samples are taken through an intravenous (IV) line instead of reinserting the needle each time. The test takes between 2 and 5 hours.The procedure is done the following way:An IV is usually placed in a vein, most often the inside of the elbow or the back of the hand. The site is first cleaned with germ-killing medicine (antiseptic). The first sample is drawn early in the morning. Medicine is given through the vein. This medicine stimulates the pituitary gland to release GH. Several medicines are available. The health care provider will decide which medicine is best. Additional blood samples are drawn over the next few hours. After the last sample is taken, the IV line is removed. Pressure is applied to stop any bleeding. How to Prepare for the Test DO NOT eat for 10 to 12 hours before the test. Eating food can change the test results.Some medicines can affect the test results. Ask your provider if you should stop taking any of your medicines before the test.If your child will have this test, explain how the test will feel. You may want to demonstrate on a doll. The more familiar your child is with what will happen and the purpose of the procedure, the less anxiety they will feel. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed This test is most often done to find out whether a growth hormone deficiency (GH deficiency) is causing slowed growth.Growth hormone deficiencyGrowth hormone deficiency means the pituitary gland does not make enough growth hormone.ImageRead Article Now Book Mark Article Normal Results Normal results include:Normal peak value, at least 10 ng/mL (10 µg/L) Indeterminate, 5 to 10 ng/mL (5 to 10 µg/L) Subnormal, 5 ng/mL (5 µg/L)A normal value rules out hGH deficiency. In some laboratories, the normal level is 7 ng/mL (7 µg/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean If this test does not raise GH levels, there is a reduced amount of hGH stored in the anterior pituitary.AnteriorAnterior means "in front of" or "the front surface of. " It usually refers to the front side of the body. For example, your knee caps are on the ant...ImageRead Article Now Book Mark Article In children, this results in GH deficiency. In adults, it may be linked to adult GH deficiency. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Multiple punctures to locate veins Fainting or feeling lightheaded Hematoma (blood accumulating under the skin) HematomaBleeding into the skin can occur from broken blood vessels that form tiny red dots (called petechiae). Blood also can collect under the tissue in la...ImageRead Article Now Book Mark Article Infection (a slight risk any time the skin is broken) Medicines that stimulate the pituitary during the test may cause side effects. The provider can tell you more about this.Open ReferencesReferencesAlatzoglou KS, Dattani MT. Growth hormone deficiency in children. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 23.Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 25.Patterson BC, Felner EI. Hypopituitarism. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 573.AllVideoImagesTogGrowth hormone stimulation test - illustration The growth hormone stimulation test is usually performed to identify if hGH (human growth hormone) is deficient. The test is performed by administering the amino acid arginine in a vein to raise hGH levels. The test measures the ability of the pituitary to secrete growth hormone in response to the arginine. Lack of hGH can cause growth retardation in infants and children.Growth hormone stimulation testillustrationGrowth hormone stimulation test - illustration The growth hormone stimulation test is usually performed to identify if hGH (human growth hormone) is deficient. The test is performed by administering the amino acid arginine in a vein to raise hGH levels. The test measures the ability of the pituitary to secrete growth hormone in response to the arginine. Lack of hGH can cause growth retardation in infants and children.Growth hormone stimulation testillustrationA Closer Look Diabetes - type 2(In-Depth)Infertility in women(In-Depth)Amenorrhea(Alt. Medicine)Angina(Alt. Medicine)Epilepsy(In-Depth)Fibromyalgia(In-Depth)Rubella(Alt. Medicine)Rheumatoid arthritis(In-Depth)Insomnia(In-Depth) Tests for Growth hormone stimulation test Growth hormone stimulation testGrowth hormone testCortisol blood testHormone levelsRelated Information Growth hormone test(Medical Test)Anterior(Special Topic)Growth hormone deficiency - children(Condition) Review Date: 8/10/2021 Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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