BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuLeucine aminopeptidase blood testSerum leucine aminopeptidase; LAP - serumThe leucine aminopeptidase (LAP) test measures how much of this enzyme is in your blood.EnzymeEnzymes are complex proteins that cause a specific chemical change in all parts of the body. For example, they can help break down the foods we eat ...Read Article Now Book Mark Article Your urine can also be checked for LAP.UrineLeucine aminopeptidase is a type of protein called an enzyme. It is normally found in liver cells and cells of the small intestine. This test is us...ImageRead Article Now Book Mark Article How the Test is Performed A blood sample is needed. Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test You need to fast for 8 hours before the test. This means you can't eat or drink anything during the 8 hours. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed LAP is a type of protein called an enzyme. This enzyme is normally found in cells of the liver, bile, blood, urine and the placenta.Your health care provider may order this test to check if your liver is damaged. Too much LAP is released into your blood when you have a liver tumor or damage to your liver cells.This test is not done very often. Other tests, such as gamma-glutamyl transferase, are as accurate and easier to get.Gamma-glutamyl transferaseThe gamma-glutamyl transferase (GGT) blood test measures the level of the enzyme GGT in the blood.Read Article Now Book Mark Article Normal Results Normal range is:Male: 80 to 200 U/mL Female: 75 to 185 U/mLNormal value ranges may vary slightly. Some labs use different measurement methods. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An abnormal result may be a sign of:Bile flow from the liver is blocked (cholestasis) CholestasisCholestasis is any condition in which the flow of bile from the liver is slowed or blocked.ImageRead Article Now Book Mark Article Cirrhosis (scarring of the liver and poor liver function) CirrhosisCirrhosis is scarring of the liver and poor liver function. It is the last stage of chronic liver disease.ImageRead Article Now Book Mark Article Hepatitis (inflamed liver) HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Liver cancer Liver ischemia (reduced blood flow to the liver) Liver necrosis (death of liver tissue) NecrosisNecrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necro...ImageRead Article Now Book Mark Article Liver tumor Liver tumorHepatocellular carcinoma is cancer that starts in the liver.ImageRead Article Now Book Mark Article Use of drugs that are toxic to the liver Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesChernecky CC, Berger BJ. Leucine aminopeptidase (LAP) - blood. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:714-715.Daniels L, Khalili M, Gordstein E, Bluth MH, Browne WB, Pincus MR. Evaluation of liver function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 22.Korneblat KM, Berk PD. Approach to the patient with jaundice or abnormal liver tests. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 138.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Leucine aminopeptidase blood test Leucine aminopeptidase blood testLeucine aminopeptidase - urineRelated Information Enzyme(Special Topic)Alanine transaminase (ALT) blood test(Medical Test)Aspartate aminotransferase (AST) blood test(Medical Test)ALP - blood test(Medical Test)Lactate dehydrogenase test(Medical Test)Gamma-glutamyl transferase (GGT) blood test(Medical Test)Leucine aminopeptidase - urine(Medical Test)Cholestasis(Condition)Cirrhosis(Condition)Hepatic(Special Topic)Cirrhosis(In-Depth)Hepatitis(In-Depth) Review Date: 1/24/2021 Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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