BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuGlucose-6-phosphate dehydrogenase testRBC G6PD test; G6PD screenGlucose-6-phosphate dehydrogenase (G6PD) is a protein that helps red blood cells work properly. The G6PD test looks at the amount (activity) of this substance in red blood cells. How the Test is Performed A blood sample is needed.Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.Read Article Now Book Mark Article How to Prepare for the Test No special preparation is usually necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed Your health care provider may recommend this test if you have signs of G6PD deficiency. This means you do not have enough G6PD activity.G6PD deficiencyGlucose-6-phosphate dehydrogenase (G6PD) deficiency is a condition in which red blood cells break down when the body is exposed to certain drugs or t...Read Article Now Book Mark Article Too little G6PD activity leads to the destruction of red blood cells. This process is called hemolysis. When this process is actively occurring, it is called a hemolytic episode.HemolysisHemolysis is the breakdown of red blood cells.Read Article Now Book Mark Article Hemolytic episodes can be triggered by infections, certain foods (such as fava beans), and certain medicines, including:Drugs used to reduce fever Nitrofurantoin Phenacetin Primaquine Sulfonamides Thiazide diuretics Tolbutamide Quinidine Normal Results Normal values vary and depend upon the laboratory used. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean Abnormal results mean you have a G6PD deficiency. This can cause hemolytic anemia in certain conditions.Hemolytic anemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Normally, red ...Read Article Now Book Mark Article Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood buildup under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesChernecky CC, Berger BJ. Glucose-6-phosphate dehydrogenase (G6PD, G-6-PD), quantitative - blood. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:594-595.Gallagher PG. Hemolytic anemias: red blood cell membrane and metabolic defects. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap152.AllVideoImagesTog Tests for Glucose-6-phosphate dehydrogenase test Glucose-6-phosphate dehydrogenase testNewborn screening testsRelated Information Enzyme(Special Topic)Glucose-6-phosphate dehydrogenase deficiency(Condition)Hemoglobin(Medical Test) Review Date: 2/6/2020 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.