BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuHam testAcid hemolysin test; Paroxysmal nocturnal hemoglobinuria - Ham test; PNH - Ham testThe Ham test is a blood test to diagnose paroxysmal nocturnal hemoglobinuria (PNH). This rare condition causes red blood cells to die before they should. The Ham test checks whether red blood cells become more fragile when they are placed in mild acid.Paroxysmal nocturnal hemoglobinuriaParoxysmal nocturnal hemoglobinuria is a rare disease in which red blood cells break down earlier than normal.Read Article Now Book Mark Article Today, the Ham test has been replaced by a test that uses flow cytometry to diagnose PNH.Open ReferencesReferencesBrodsky RA. Paroxysmal nocturnal hemoglobinuria. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 31.AllVideoImagesTog Tests for Ham test Ham testRelated Information Paroxysmal nocturnal hemoglobinuria (PNH)(Condition)Complement(Medical Test)Anemia(Condition)Sugar-water hemolysis test(Medical Test)Erythropoietin test(Medical Test)Anemia(In-Depth) Review Date: 2/6/2020 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.