BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuParathyroid hormone-related protein blood testPTHrp; PTH-related peptideThe parathyroid hormone-related protein (PTH-RP) test measures the level of a hormone in the blood, called parathyroid hormone-related protein. How the Test is Performed A blood sample is needed.Blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.Read Article Now Book Mark Article How to Prepare for the Test No special preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or slight bruising. This soon goes away. Why the Test is Performed This test is done to find out whether a high blood calcium level is caused by an increase in PTH-related protein.High blood calcium levelHypercalcemia means you have too much calcium in your blood.Read Article Now Book Mark Article Normal Results No detectable (or minimal) PTH-like protein is normal.Women who are breastfeeding may have detectable PTH-related protein values. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your doctor about the meaning of your specific test results. What Abnormal Results Mean An increased level of PTH-related protein with a high blood calcium level is usually caused by cancer.PTH-related protein can be produced by many different kinds of cancers, including those of the lung, breast, head, neck, bladder, and ovaries. In about two thirds of people with cancer who have a high calcium level, a high level of PTH-related protein is the cause. This condition is called humoral hypercalcemia of malignancy (HHM) or paraneoplastic hypercalcemia. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesBringhurst FR, Demay MB, Kronenberg HM. Hormones and disorders of mineral metabolism. In: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 29.Thakker RV. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 232.AllVideoImagesTogA Closer Look Hyperparathyroidism(Alt. Medicine)Hypothyroidism(In-Depth)Kidney stones(In-Depth)Osteoporosis(Alt. Medicine)Osteoporosis(In-Depth)Colorectal cancer(Alt. Medicine) Tests for Parathyroid hormone-related protein blood test Parathyroid hormone-related protein blood testParathyroid hormone (PTH) blood testProlactin blood testFree T4 testALP isoenzyme testRelated Information Parathyroid hormone (PTH) blood test(Medical Test)Calcium - ionized(Medical Test) Review Date: 5/13/2021 Reviewed By: Brent Wisse, MD, Board Certified in Metabolism/Endocrinology, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.