BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuFluorescein angiographyRetinal photography; Eye angiography; Angiography - fluoresceinFluorescein angiography is an eye test that uses a special dye and camera to look at blood flow in the retina and choroid. These are the two layers in the back of the eye.RetinaThe retina is the light-sensitive layer of tissue at the back of the eyeball. Images that come through the eye's lens are focused on the retina. Th...ImageRead Article Now Book Mark Article ChoroidThe choroid is the layer of blood vessels and connective tissue between the white of the eye and retina (at the back of the eye). It is part of the ...ImageRead Article Now Book Mark Article How the Test is Performed You will be given eye drops that make your pupil dilate. You will be asked to place your chin on a chin rest and your forehead against a support bar to keep your head still during the test.The health care provider will take pictures of the inside of your eye. After the first group of pictures is taken, a dye called fluorescein is injected into a vein. Most often it is injected at the inside of your elbow. A camera-like device takes pictures as the dye moves through the blood vessels in the back of your eye.A newer method called ultra-widefield fluorescein angiography can provide more information about certain diseases than regular angiography. How to Prepare for the Test You will need someone to drive you home. Your vision may be blurry for up to 12 hours after the test.You may be told to stop taking medicines that could affect the test results. Tell your provider about any allergies, particularly reactions to iodine.You must sign an informed consent form. You must remove contact lenses before the test.Tell the provider if you may be pregnant. How the Test will Feel When the needle is inserted, some people feel slight pain. Others feel only a prick or sting. Afterward, there may be some throbbing.When the dye is injected, you may have mild nausea and a warm feeling in your body. These symptoms go away quickly most of the time. The dye will cause your urine to be darker. It may be orange in color for a day or two after the test. Why the Test is Performed This test is done to see if there is proper blood flow in the blood vessels in the two layers in the back of your eye (the retina and choroid). It can also be used to diagnose problems in the eye or to determine how well certain eye treatments are working. Normal Results A normal result means the vessels appear a normal size, there are no new abnormal vessels, and there are no blockages or leakages. What Abnormal Results Mean If blockage or leakage is present, the pictures will map the location for possible treatment.An abnormal value on a fluorescein angiography may be due to:Blood flow (circulatory) problems, such as blockage of the arteries or veins Cancer CancerCancer is the uncontrolled growth of abnormal cells in the body. Cancerous cells are also called malignant cells.Read Article Now Book Mark Article Diabetic or other retinopathy High blood pressure Inflammation or edema EdemaSwelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a ...ImageRead Article Now Book Mark Article Macular degeneration Macular degenerationMacular degeneration is an eye disorder that slowly destroys sharp, central vision. This makes it difficult to see fine details and read. The diseas...ImageRead Article Now Book Mark Article Microaneurysms -- enlargement of capillaries in the retina Tumors TumorsA tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).Read Article Now Book Mark Article Swelling of the optic disc The test may also be done if you have: Retinal detachment Retinal detachmentRetinal detachment is a separation of the light-sensitive membrane (retina) in the back of the eye from its supporting layers.ImageRead Article Now Book Mark Article Retinitis pigmentosaRetinitis pigmentosaRetinitis pigmentosa is an eye disease in which there is damage to the retina. The retina is the layer of tissue at the back of the inner eye. This...ImageRead Article Now Book Mark Article Risks There is a slight chance of infection any time the skin is broken. Rarely, a person is overly sensitive to the dye and may experience:Dizziness or faintness Dry mouth or increased salivation Hives HivesHives are raised, often itchy, red bumps (welts) on the surface of the skin. They can be an allergic reaction to food or medicine. They can also ap...ImageRead Article Now Book Mark Article Increased heart rate Heart rateThe pulse is the number of heartbeats per minute.ImageRead Article Now Book Mark Article Metallic taste in mouth Nausea and vomiting Sneezing Serious allergic reactions are rare. Considerations The test results are harder to interpret in people with cataracts. Blood flow problems shown on fluorescein angiography may suggest blood flow problems in other parts of the body.Open ReferencesReferencesFeinstein E, Olson JL, Mandava N. Camera-based ancillary retinal testing: autofluorescence, fluorescein, and indocyanine green angiography. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 6.6.Haug S, Fu AD, Johnson RN, McDonald HR, et al. Fluorescein angiography: basic principles and interpretation. In: Schachat AP, Sadda SVR, Hinton DR, Wilkinson CP, Wiedemann P, eds. Ryan's Retina. 6th ed. Philadelphia, PA: Elsevier; 2018:chap 1.Karampelas M, Sim DA, Chu C, et al. Quantitative analysis of peripheral vasculitis, ischemia, and vascular leakage in uveitis using ultra-widefield fluorescein angiography. Am J Ophthalmol. 2015;159(6):1161-1168. PMID: 25709064 www.ncbi.nlm.nih.gov/pubmed/25709064/.Taha NM, Asklany HT, Mahmoud AH, et al. Retinal fluorescein angiography: a sensitive and specific tool to predict coronary slow flow. Egypt Heart J. 2018;70(3):167-171. PMID: 30190642 pubmed.ncbi.nlm.nih.gov/30190642/.AllVideoImagesTogRetinal dye injection - illustration Retinal dye injection is used to determine if there is proper circulation in the retinal vessels in the eye. When dye is injected in a vein in the arm, a rapid series of photographs are taken. Among other things this test can detect problems such as blockages or tumors.Retinal dye injectionillustrationRetinal dye injection - illustration Retinal dye injection is used to determine if there is proper circulation in the retinal vessels in the eye. When dye is injected in a vein in the arm, a rapid series of photographs are taken. Among other things this test can detect problems such as blockages or tumors.Retinal dye injectionillustration Tests for Fluorescein angiography Fluorescein angiographyArteriogramRelated Information Retina(Special Topic)Retinopathy of prematurity(Condition)Diabetes and eye disease(Condition)High blood pressure and eye disease(Condition)Age-related macular degeneration(Condition)Retinal detachment(Condition)Retinal artery occlusion(Condition)Retinitis pigmentosa(Condition) Review Date: 8/18/2020 Reviewed By: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.