BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuBrain tumor - primary - adultsGlioblastoma multiforme - adults; Ependymoma - adults; Glioma - adults; Astrocytoma - adults; Medulloblastoma - adults; Neuroglioma - adults; Oligodendroglioma - adults; Lymphoma - adults; Vestibular schwannoma (acoustic neuroma) - adults; Meningioma - adults; Cancer - brain tumor (adults)A primary brain tumor is a group (mass) of abnormal cells that start in the brain. Causes Primary brain tumors include any tumor that starts in the brain. Primary brain tumors can start from brain cells, the membranes around the brain (meninges), nerves, or glands.TumorA tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).Read Article Now Book Mark Article Tumors can directly destroy brain cells. They can also damage cells by producing inflammation, placing pressure on other parts of the brain, and increasing pressure within the skull.Pressure within the skullIncreased intracranial pressure is a rise in the pressure inside the skull that can result from or cause brain injury.ImageRead Article Now Book Mark Article The cause of primary brain tumors is unknown. There are many risk factors that could play a role:Radiation therapy used to treat brain cancers increases the risk of brain tumors up to 20 or 30 years later. Some inherited conditions increase the risk of brain tumors, including neurofibromatosis, Von Hippel-Lindau syndrome, Li-Fraumeni syndrome, and Turcot syndrome. Lymphomas that begin in the brain in people with a weakened immune system are sometimes linked to infection by the Epstein-Barr virus. These have not proven to be risk factors:Exposure to radiation at work, or to power lines, cell phones, cordless phones, or wireless devices Head injuries Smoking Hormone therapy SPECIFIC TUMOR TYPESBrain tumors are classified depending on: Location of the tumor Type of tissue involved Whether they are noncancerous (benign) or cancerous (malignant) Other factors Sometimes, tumors that start out less aggressive can change their biologic behavior and become more aggressive.Tumors can occur at any age, but many types are most common in a certain age group. In adults, gliomas and meningiomas are the most common.Gliomas come from glial cells such as astrocytes, oligodendrocytes, and ependymal cells. Gliomas are divided into three types:Astrocytic tumors include astrocytomas (can be noncancerous), anaplastic astrocytomas, and glioblastomas. Oligodendroglial tumors. Some primary brain tumors are made up of both astrocytic and oligodendrocytic tumors. These are called mixed gliomas. Glioblastomas are the most aggressive type of primary brain tumor. Meningiomas and schwannomas are two other types of brain tumors. These tumors:Occur most often between ages 40 and 70. Are usually noncancerous, but can still cause serious complications and death from their size or location. Some are cancerous and aggressive. Other primary brain tumors in adults are rare. These include:Ependymomas Craniopharyngiomas Pituitary tumors Primary (central nervous system - CNS) lymphoma Pineal gland tumors Primary germ cell tumors of the brain Symptoms Some tumors do not cause symptoms until they are very large. Other tumors have symptoms that develop slowly.Symptoms depend on the tumor's size, location, how far it has spread, and whether there is brain swelling. The most common symptoms are:Changes in the person's mental function Headaches Seizures (especially in older adults) Weakness in one part of the body Headaches caused by brain tumors may:Be worse when the person wakes up in the morning, and clear up in a few hours Occur during sleep Occur with vomiting, confusion, double vision, weakness, or numbness Get worse with coughing or exercise, or with a change in body position Other symptoms can include:Change in alertness (including sleepiness, unconsciousness, and coma) Changes in hearing, taste, or smell Changes that affect touch and the ability to feel pain, pressure, different temperatures, or other stimuli Confusion or memory loss Difficulty swallowing Difficulty swallowingDifficulty with swallowing is the feeling that food or liquid is stuck in the throat or at any point before the food enters the stomach. This proble...ImageRead Article Now Book Mark Article Difficulty writing or reading Dizziness or abnormal sensation of movement (vertigo) Eye problems such as eyelid drooping, pupils of different sizes, uncontrollable eye movement, vision difficulties (including decreased vision, double vision, or total loss of vision) Hand tremor Lack of control over the bladder or bowels Loss of balance or coordination, clumsiness, trouble walking Muscle weakness in the face, arm, or leg (usually on just one side) Numbness or tingling on one side of the body Personality, mood, behavior, or emotional changes Trouble speaking or understanding others who are speaking Other symptoms that may occur with a pituitary tumor:Pituitary tumorA pituitary tumor is an abnormal growth in the pituitary gland. The pituitary is a small gland at the base of the brain. It regulates the body's ba...ImageRead Article Now Book Mark Article Abnormal nipple discharge Absent menstruation (periods) Breast development in men Enlarged hands, feet Excessive body hair Facial changes Low blood pressure Low blood pressureLow blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body do not get enough ...Read Article Now Book Mark Article Obesity Sensitivity to heat or cold Exams and Tests The following tests may confirm the presence of a brain tumor and find its location:CT scan of the head CT scan of the headA head computed tomography (CT) scan uses many x-rays to create pictures of the head, including the skull, brain, eye sockets, and sinuses.ImageRead Article Now Book Mark Article EEG (to measure the electrical activity of the brain) EEGAn electroencephalogram (EEG) is a test to measure the electrical activity of the brain.ImageRead Article Now Book Mark Article Examination of tissue removed from the tumor during surgery or CT-guided biopsy (may confirm the type of tumor) BiopsyA biopsy is the removal of a small piece of tissue for laboratory examination.Read Article Now Book Mark Article Examination of the cerebral spinal fluid (CSF) (may show cancerous cells) MRI of the headMRI of the headA head MRI (magnetic resonance imaging) is an imaging test that uses powerful magnets and radio waves to create pictures of the brain and surrounding...ImageRead Article Now Book Mark Article Treatment Treatment can involve surgery, radiation therapy, and chemotherapy. Brain tumors are best treated by a team that includes:Neuro-oncologist Neurosurgeon Medical oncologist Radiation oncologist Other health care providers, such as neurologists and social workersEarly treatment often improves the chance of a good outcome. Treatment depends on the size and type of tumor and your general health. Goals of treatment may be to cure the tumor, relieve symptoms, and improve brain function or comfort.Surgery is often needed for most primary brain tumors. Some tumors may be completely removed. Those that are deep inside the brain or that enter brain tissue may be debulked instead of removed. Debulking is a procedure to reduce the tumor's size.Tumors can be hard to remove completely by surgery alone. This is because the tumor invades surrounding brain tissue much like roots from a plant spread through soil. When the tumor cannot be removed, surgery may still help reduce pressure and relieve symptoms.Radiation therapy is used for certain tumors.Radiation therapyRadiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.ImageRead Article Now Book Mark Article Chemotherapy may be used with surgery or radiation treatment.Other medicines used to treat primary brain tumors in children may include:Medicines to reduce brain swelling and pressure Anticonvulsants to reduce seizures Pain medicinesComfort measures, safety measures, physical therapy, and occupational therapy may be needed to improve quality of life. Counseling, support groups, and similar measures can help people cope with the disorder.You may consider enrolling in a clinical trial after talking with your treatment team. Possible Complications Complications that may result from brain tumors include:Brain herniation (often fatal) Brain herniationBrain herniation is the shifting of the brain tissue from one space in the brain to another through various folds and openings.ImageRead Article Now Book Mark Article Loss of ability to interact or function Permanent, worsening, and severe loss of brain function Return of tumor growth Side effects of medicines, including chemotherapy Side effects of radiation treatments When to Contact a Medical Professional Contact your provider if you develop any new, persistent headaches or other symptoms of a brain tumor.Contact your provider or go to the emergency room if you start having seizures, or suddenly develop stupor (reduced alertness), vision changes, or speech changes.StuporDecreased alertness is the most severe state of reduced awareness and is a serious condition. A coma is a state of decreased alertness from which a p...Read Article Now Book Mark Article Open ReferencesReferencesDorsey JF, Salinas RD, Dang M, et al. Cancer of the central nervous system. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 63.Michaud DS. Epidemiology of brain tumors. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 71.National Cancer Institute website. Adult central nervous system tumors treatment (PDQ) - health professional version. www.cancer.gov/types/brain/hp/adult-brain-treatment-pdq. Updated January 18, 2022. Accessed May 9, 2022.National Comprehensive Cancer Network website. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): central nervous system cancers. Version 2.2021. www.nccn.org/professionals/physician_gls/pdf/cns.pdf. Updated September 8, 2021. Accessed December 14, 2021.AllVideoImagesTogBrain tumor - illustration Brain tumors are classified depending on the exact site of the tumor, the type of tissue involved, benign or malignant tendencies of the tumor, and other factors. Primary brain tumors can arise from the brain cells, the meninges (membranes around the brain), nerves, or glands.Brain tumorillustrationBrain tumor - illustration Brain tumors are classified depending on the exact site of the tumor, the type of tissue involved, benign or malignant tendencies of the tumor, and other factors. Primary brain tumors can arise from the brain cells, the meninges (membranes around the brain), nerves, or glands.Brain tumorillustrationA Closer Look Brain tumors - primary(In-Depth)Stroke(Alt. 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