BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAspirin overdoseAcetylsalicylic acid overdoseAspirin is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate aches and pains, swelling, and fever.Aspirin overdose occurs when someone accidentally or intentionally takes more than the recommended amount of this medicine. This can happen in two ways:If a person takes a very large dose of aspirin at one time, it is called an acute overdose. If a normal daily dose of aspirin builds up in the body over time and causes symptoms, it is called a chronic overdose. This may happen if your kidneys do not work correctly or when you are dehydrated. Chronic overdoses are usually seen in older people during hot weather.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Acetylsalicylic acid Where Found Aspirin is also known as acetylsalicylic acid and can be found in many prescription and over-the-counter pain relievers, including:Alka Seltzer Anacin Bayer Bufferin Ecotrin Excedrin Fiorinal Percodan St. Joseph Low Dose Aspirin Lanorinal Orphengesic VazaloreNote: This list may not be all-inclusive. Symptoms Airways and lungs:Rapid breathing Slow, labored breathing Wheezing Eyes, ears, nose, and throat:Ringing in the ears Ringing in the earsTinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...Read Article Now Book Mark Article Blurred vision Nervous system:Agitation, confusion, incoherence (not understandable) Collapse Lack of responsiveness (coma) Seizures SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Headache (severe) Unsteadiness, problems moving Skin:Rash Stomach and intestines:Diarrhea Heartburn Nausea, vomiting (sometimes bloody) Stomach pain (possible bleeding in the stomach and intestines) Symptoms of chronic overdose may include:Fatigue Slight fever Confusion Collapse Rapid heart beat Uncontrollable rapid breathingRapid breathingHyperventilation is rapid and deep breathing. It is also called overbreathing, and it may leave you feeling breathless.Read Article Now Book Mark Article Before Calling Emergency The following information is helpful for emergency assistance:Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed However, DO NOT delay calling for help if this information is not immediately available. Poison Control The local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.You can also get online poison help now at Poisonhelp.org. Just enter the product, poison, or medicine to get expert help.For more information about America's Poison Centers, go to poisoncenters.org.If you go to the emergency room, take the container with you, if possible. What to Expect at the Emergency Room The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Symptoms will be treated as appropriate. The person may receive:Activated charcoal Airway support, including oxygen, breathing tube through the mouth (intubation), and ventilator (breathing machine) Blood and urine tests including a blood salicylate level Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article ECG (electrocardiogram, or heart tracing) ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Fluids through the vein (intravenous or IV) Laxative Medicines to treat symptomsOther medicines may be given through a vein, including potassium salt and sodium bicarbonate, which helps the body remove aspirin that has already been absorbed.If these treatments do not work or the overdose is extremely severe, hemodialysis (kidney machine) may be needed to reverse the condition.HemodialysisFacioscapulohumeral muscular dystrophy is a condition that causes muscle weakness and loss of muscle tissue that gets worse over time.Read Article Now Book Mark Article In rare cases, a breathing machine may be needed. Many poisoning experts think this causes more harm than good, so it is only used as a last resort. Outlook (Prognosis) A toxic dose of aspirin is 200 to 300 mg/kg (milligrams per kilogram of body weight), and ingestion of 500 mg/kg is potentially lethal. In chronic overdose a lower level of aspirin in the body can result in serious illness. Much lower levels can affect children.If treatment is delayed or the overdose is large enough, symptoms will continue to get worse. Breathing becomes extremely fast or may stop. Seizures, high fevers, or death may occur.How well you do depends greatly on how much aspirin your body has absorbed and how much is flowing through your blood. If you take a large amount of aspirin but come quickly to the emergency room, treatments may help keep your blood levels of aspirin very low. If you do not get to the emergency room fast enough, the level of aspirin in your blood can become dangerously high.Open ReferencesReferencesAronson JK. Acetylsalicylic acid. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:26-52.Bluth MH, Pincus MR, Abraham NZ. Toxicology and therapeutic drug monitoring. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 24.Hatten BW. Aspirin and nonsteroidal agents. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 139.Nelson LS, Calello DP. Acute poisoning. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 96.Theobald JL, Corcoran JN. Poisoning. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 94.AllVideoImagesTogRelated Information Review Date: 1/8/2025 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. 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Aspirin overdoseAcetylsalicylic acid overdoseAspirin is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate aches and pains, swelling, and fever.Aspirin overdose occurs when someone accidentally or intentionally takes more than the recommended amount of this medicine. This can happen in two ways:If a person takes a very large dose of aspirin at one time, it is called an acute overdose. If a normal daily dose of aspirin builds up in the body over time and causes symptoms, it is called a chronic overdose. This may happen if your kidneys do not work correctly or when you are dehydrated. Chronic overdoses are usually seen in older people during hot weather.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Acetylsalicylic acid Where Found Aspirin is also known as acetylsalicylic acid and can be found in many prescription and over-the-counter pain relievers, including:Alka Seltzer Anacin Bayer Bufferin Ecotrin Excedrin Fiorinal Percodan St. Joseph Low Dose Aspirin Lanorinal Orphengesic VazaloreNote: This list may not be all-inclusive. Symptoms Airways and lungs:Rapid breathing Slow, labored breathing Wheezing Eyes, ears, nose, and throat:Ringing in the ears Ringing in the earsTinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...Read Article Now Book Mark Article Blurred vision Nervous system:Agitation, confusion, incoherence (not understandable) Collapse Lack of responsiveness (coma) Seizures SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Headache (severe) Unsteadiness, problems moving Skin:Rash Stomach and intestines:Diarrhea Heartburn Nausea, vomiting (sometimes bloody) Stomach pain (possible bleeding in the stomach and intestines) Symptoms of chronic overdose may include:Fatigue Slight fever Confusion Collapse Rapid heart beat Uncontrollable rapid breathingRapid breathingHyperventilation is rapid and deep breathing. It is also called overbreathing, and it may leave you feeling breathless.Read Article Now Book Mark Article Before Calling Emergency The following information is helpful for emergency assistance:Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed However, DO NOT delay calling for help if this information is not immediately available. Poison Control The local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.You can also get online poison help now at Poisonhelp.org. Just enter the product, poison, or medicine to get expert help.For more information about America's Poison Centers, go to poisoncenters.org.If you go to the emergency room, take the container with you, if possible. What to Expect at the Emergency Room The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Symptoms will be treated as appropriate. The person may receive:Activated charcoal Airway support, including oxygen, breathing tube through the mouth (intubation), and ventilator (breathing machine) Blood and urine tests including a blood salicylate level Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article ECG (electrocardiogram, or heart tracing) ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Fluids through the vein (intravenous or IV) Laxative Medicines to treat symptomsOther medicines may be given through a vein, including potassium salt and sodium bicarbonate, which helps the body remove aspirin that has already been absorbed.If these treatments do not work or the overdose is extremely severe, hemodialysis (kidney machine) may be needed to reverse the condition.HemodialysisFacioscapulohumeral muscular dystrophy is a condition that causes muscle weakness and loss of muscle tissue that gets worse over time.Read Article Now Book Mark Article In rare cases, a breathing machine may be needed. Many poisoning experts think this causes more harm than good, so it is only used as a last resort. Outlook (Prognosis) A toxic dose of aspirin is 200 to 300 mg/kg (milligrams per kilogram of body weight), and ingestion of 500 mg/kg is potentially lethal. In chronic overdose a lower level of aspirin in the body can result in serious illness. Much lower levels can affect children.If treatment is delayed or the overdose is large enough, symptoms will continue to get worse. Breathing becomes extremely fast or may stop. Seizures, high fevers, or death may occur.How well you do depends greatly on how much aspirin your body has absorbed and how much is flowing through your blood. If you take a large amount of aspirin but come quickly to the emergency room, treatments may help keep your blood levels of aspirin very low. If you do not get to the emergency room fast enough, the level of aspirin in your blood can become dangerously high.Open ReferencesReferencesAronson JK. Acetylsalicylic acid. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:26-52.Bluth MH, Pincus MR, Abraham NZ. Toxicology and therapeutic drug monitoring. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 24.Hatten BW. Aspirin and nonsteroidal agents. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 139.Nelson LS, Calello DP. Acute poisoning. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 96.Theobald JL, Corcoran JN. Poisoning. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 94.
