BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuLactate dehydrogenase testLDH test; Lactic acid dehydrogenase testLactate dehydrogenase (LDH) is a protein that helps produce energy in the body. An LDH test measures the amount of LDH in the blood. How the Test is Performed A blood sample is needed.Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No specific preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed LDH is most often measured to check for tissue damage. LDH is in many body tissues, especially the heart, liver, kidney, muscles, brain, blood cells, and lungs.Other conditions for which the test may be done include:Low red blood cell count (anemia) AnemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Different type...ImageRead Article Now Book Mark Article Cancer, including blood cancer (leukemia) or lymph cancer (lymphoma) LeukemiaLeukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are ...ImageRead Article Now Book Mark Article Normal Results Normal value range is 125 to 220 international units per liter (IU/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific results. What Abnormal Results Mean A higher-than-normal level may indicate:Blood flow deficiency (ischemia) Heart attack Heart attackMost heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. ...ImageRead Article Now Book Mark Article Hemolytic anemia Hemolytic anemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Normally, red ...ImageRead Article Now Book Mark Article Infectious mononucleosis Infectious mononucleosisMononucleosis, or mono, is a viral infection that causes fever, sore throat, and swollen lymph glands, most often in the neck.ImageRead Article Now Book Mark Article Leukemia or lymphoma Liver disease (for example, hepatitis) Liver diseaseThe term "liver disease" applies to many conditions that stop the liver from working or prevent it from functioning well. Abdominal pain or swelling...ImageRead Article Now Book Mark Article HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Low blood pressure Muscle injury Muscle weakness and loss of muscle tissue (muscular dystrophy) Muscular dystrophyMuscular dystrophy (MD) is a group of inherited disorders that cause muscle weakness and loss of muscle tissue, which get worse over time.ImageRead Article Now Book Mark Article New abnormal tissue formation (usually cancer) Pancreatitis Stroke StrokeA stroke occurs when blood flow to a part of the brain stops. A stroke is sometimes called a "brain attack. " If blood flow is cut off for longer th...ImageRead Article Now Book Mark Article Tissue deathIf your LDH level is high, your provider may recommend an LDH isoenzymes test to determine the location of any tissue damage.LDH isoenzymes testThe lactate dehydrogenase (LDH) isoenzyme test checks how much of the different types of LDH, called isoenzymes, are present in the blood.ImageRead Article Now Book Mark Article Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded FaintingFainting is a brief loss of consciousness due to a drop in blood flow to the brain. The episode most often lasts less than a couple of minutes and y...Read Article Now Book Mark Article Multiple punctures to locate veins Hematoma (blood buildup under the skin) HematomaA bruise is an area of skin discoloration. A bruise occurs when small blood vessels break and leak their contents into the soft tissue beneath the s...ImageRead Article Now Book Mark Article Infection (a slight risk any time the skin is broken)Open ReferencesReferencesPanteghini M. Serum enzymes. In: Rifai N, Chiu RWK, Young I, Burnham CD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 32.Pincus MR, Carty RP. Clinical enzymology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 21.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Lactate dehydrogenase test Lactate dehydrogenase testLDH isoenzyme blood testAldolase blood testSynovial fluid analysisCSF analysisRelated Information LDH isoenzyme blood test(Medical Test)Enzyme(Special Topic)Lactic acid test(Medical Test)Stroke(Condition)Heart attack(Condition)Hemolytic anemia(Condition)Mononucleosis(Condition)Liver disease(Condition)Hepatitis(Condition)Muscular dystrophy(Condition)Stroke - InDepth(In-Depth)Heart attack and acute coronary syndrome - InDepth(In-Depth)Hepatitis - InDepth(In-Depth) Review Date: 3/31/2024 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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Lactate dehydrogenase testLDH test; Lactic acid dehydrogenase testLactate dehydrogenase (LDH) is a protein that helps produce energy in the body. An LDH test measures the amount of LDH in the blood. How the Test is Performed A blood sample is needed.Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No specific preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed LDH is most often measured to check for tissue damage. LDH is in many body tissues, especially the heart, liver, kidney, muscles, brain, blood cells, and lungs.Other conditions for which the test may be done include:Low red blood cell count (anemia) AnemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Different type...ImageRead Article Now Book Mark Article Cancer, including blood cancer (leukemia) or lymph cancer (lymphoma) LeukemiaLeukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are ...ImageRead Article Now Book Mark Article Normal Results Normal value range is 125 to 220 international units per liter (IU/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific results. What Abnormal Results Mean A higher-than-normal level may indicate:Blood flow deficiency (ischemia) Heart attack Heart attackMost heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. ...ImageRead Article Now Book Mark Article Hemolytic anemia Hemolytic anemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Normally, red ...ImageRead Article Now Book Mark Article Infectious mononucleosis Infectious mononucleosisMononucleosis, or mono, is a viral infection that causes fever, sore throat, and swollen lymph glands, most often in the neck.ImageRead Article Now Book Mark Article Leukemia or lymphoma Liver disease (for example, hepatitis) Liver diseaseThe term "liver disease" applies to many conditions that stop the liver from working or prevent it from functioning well. Abdominal pain or swelling...ImageRead Article Now Book Mark Article HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Low blood pressure Muscle injury Muscle weakness and loss of muscle tissue (muscular dystrophy) Muscular dystrophyMuscular dystrophy (MD) is a group of inherited disorders that cause muscle weakness and loss of muscle tissue, which get worse over time.ImageRead Article Now Book Mark Article New abnormal tissue formation (usually cancer) Pancreatitis Stroke StrokeA stroke occurs when blood flow to a part of the brain stops. A stroke is sometimes called a "brain attack. " If blood flow is cut off for longer th...ImageRead Article Now Book Mark Article Tissue deathIf your LDH level is high, your provider may recommend an LDH isoenzymes test to determine the location of any tissue damage.LDH isoenzymes testThe lactate dehydrogenase (LDH) isoenzyme test checks how much of the different types of LDH, called isoenzymes, are present in the blood.ImageRead Article Now Book Mark Article Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded FaintingFainting is a brief loss of consciousness due to a drop in blood flow to the brain. The episode most often lasts less than a couple of minutes and y...Read Article Now Book Mark Article Multiple punctures to locate veins Hematoma (blood buildup under the skin) HematomaA bruise is an area of skin discoloration. A bruise occurs when small blood vessels break and leak their contents into the soft tissue beneath the s...ImageRead Article Now Book Mark Article Infection (a slight risk any time the skin is broken)Open ReferencesReferencesPanteghini M. Serum enzymes. In: Rifai N, Chiu RWK, Young I, Burnham CD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 32.Pincus MR, Carty RP. Clinical enzymology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 21.