BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuApolipoprotein B100ApoB100; Apoprotein B100; Hypercholesterolemia - apolipoprotein B100Apolipoprotein B100 (apoB100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein (LDL).Variants in the gene that directs the body's production of apoB100 can cause a condition called familial hypercholesterolemia. This is a form of high blood cholesterol that is passed down in families (inherited).Familial hypercholesterolemiaFamilial hypercholesterolemia is a disorder that is passed down through families. It causes LDL (bad) cholesterol level to be very high. The condit...ImageRead Article Now Book Mark Article This article discusses the test used to measure the level of apoB100 in the blood.Related video goes here for no-HTML5 browsers How the Test is Performed A blood sample is needed.A blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test Your health care provider may tell you not to eat or drink anything for 4 to 6 hours before the test. How the Test will Feel When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.Previous imagePlay SlideshowStop SlideshowNext image / Why the Test is Performed Most often, this test is done to help determine the cause or specific type of high blood cholesterol. It is not clear whether the information helps improve treatment. Because of this, most health insurance companies do not pay for the test. If you do not have a diagnosis of high cholesterol or heart disease, this test may not be recommended for you. Normal Results The normal range is about 50 to 150 mg/dL.Normal value ranges may vary slightly among different laboratories. Some laboratories use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An abnormal result may mean you have high lipid (fat) levels in your blood. A medical term for this is hyperlipidemia.HyperlipidemiaCholesterol is a fat (also called a lipid) that your body needs to work properly. Too much bad cholesterol in your blood can increase your chance of...ImageRead Article Now Book Mark Article Other disorders that may be associated with high apoB100 levels include atherosclerotic vascular disease such as angina pectoris (chest pain that occurs with activity or stress) and heart attack.Angina pectorisAngina is a type of chest discomfort or pain due to poor blood flow through the blood vessels (coronary arteries) of the heart muscle (myocardium). ...ImageRead Article Now Book Mark Article Heart attackMost heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. ...ImageRead Article Now Book Mark Article Risks Risks linked with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Hematoma (blood buildup under the skin) Infection (a slight risk any time the skin is broken) Multiple punctures to locate veins Considerations Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.Open ReferencesReferencesBredefeld CL, Lau R, Hussain MM. Lipids and dyslipoproteinemia. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. St Louis, MO: Elsevier; 2022:chap 18.Genest J, Mora S, Libby P. Lipoprotein disorders and cardiovascular disease. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 27.Libby P. The vascular biology of atherosclerosis. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 24.Meeusen JW, Ueda M, Nordestgaard BG, Remaley AT. Lipids and lipoproteins. In: Rifai N, Chiu RWK, Young I, Burnham C-A D, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 36.Mora S, Martin SS. Measurement of low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol, apolipoprotein B, and low-density lipoprotein particle concentration. In: Ballantyne CM, ed. Clinical Lipidology: A Companion to Braunwald's Heart Disease. 3rd ed. Philadelphia, PA: Elsevier; 2024:chap 3.Robinson JG. Disorders of lipid metabolism. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 190.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Apolipoprotein B100 Apolipoprotein B100Related Information Triglyceride level(Medical Test)Metabolism(Special Topic)High blood cholesterol levels(Condition)Familial combined hyperlipidemia(Condition)Angina(Condition)Heart attack(Condition)Cholesterol - InDepth(In-Depth)Coronary artery disease - InDepth(In-Depth)Heart attack and acute coronary syndrome - InDepth(In-Depth) Review Date: 5/8/2024 Reviewed By: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.
Apolipoprotein B100ApoB100; Apoprotein B100; Hypercholesterolemia - apolipoprotein B100Apolipoprotein B100 (apoB100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein (LDL).Variants in the gene that directs the body's production of apoB100 can cause a condition called familial hypercholesterolemia. This is a form of high blood cholesterol that is passed down in families (inherited).Familial hypercholesterolemiaFamilial hypercholesterolemia is a disorder that is passed down through families. It causes LDL (bad) cholesterol level to be very high. The condit...ImageRead Article Now Book Mark Article This article discusses the test used to measure the level of apoB100 in the blood.Related video goes here for no-HTML5 browsers How the Test is Performed A blood sample is needed.A blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test Your health care provider may tell you not to eat or drink anything for 4 to 6 hours before the test. How the Test will Feel When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.Previous imagePlay SlideshowStop SlideshowNext image / Why the Test is Performed Most often, this test is done to help determine the cause or specific type of high blood cholesterol. It is not clear whether the information helps improve treatment. Because of this, most health insurance companies do not pay for the test. If you do not have a diagnosis of high cholesterol or heart disease, this test may not be recommended for you. Normal Results The normal range is about 50 to 150 mg/dL.Normal value ranges may vary slightly among different laboratories. Some laboratories use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An abnormal result may mean you have high lipid (fat) levels in your blood. A medical term for this is hyperlipidemia.HyperlipidemiaCholesterol is a fat (also called a lipid) that your body needs to work properly. Too much bad cholesterol in your blood can increase your chance of...ImageRead Article Now Book Mark Article Other disorders that may be associated with high apoB100 levels include atherosclerotic vascular disease such as angina pectoris (chest pain that occurs with activity or stress) and heart attack.Angina pectorisAngina is a type of chest discomfort or pain due to poor blood flow through the blood vessels (coronary arteries) of the heart muscle (myocardium). ...ImageRead Article Now Book Mark Article Heart attackMost heart attacks are caused by a blood clot that blocks one of the coronary arteries. The coronary arteries bring blood and oxygen to the heart. ...ImageRead Article Now Book Mark Article Risks Risks linked with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Hematoma (blood buildup under the skin) Infection (a slight risk any time the skin is broken) Multiple punctures to locate veins Considerations Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.Open ReferencesReferencesBredefeld CL, Lau R, Hussain MM. Lipids and dyslipoproteinemia. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. St Louis, MO: Elsevier; 2022:chap 18.Genest J, Mora S, Libby P. Lipoprotein disorders and cardiovascular disease. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 27.Libby P. The vascular biology of atherosclerosis. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 24.Meeusen JW, Ueda M, Nordestgaard BG, Remaley AT. Lipids and lipoproteins. In: Rifai N, Chiu RWK, Young I, Burnham C-A D, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 36.Mora S, Martin SS. Measurement of low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol, apolipoprotein B, and low-density lipoprotein particle concentration. In: Ballantyne CM, ed. Clinical Lipidology: A Companion to Braunwald's Heart Disease. 3rd ed. Philadelphia, PA: Elsevier; 2024:chap 3.Robinson JG. Disorders of lipid metabolism. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 190.
